Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779958 | 0.83 | SIRT2 (0.45) | SIRT2GRK2 | |
| SCHEMBL8026490 | 0.83 | AKR1C3 (0.44) | MTNR1AMTNR1BSIRT2AKR1C3USP2 | |
| SCHEMBL9779973 | 0.81 | MEN1 (0.53) | GRK2USP2 | |
| SCHEMBL8026213 | 0.80 | GAA (0.43) | MTNR1AMTNR1BSIRT2CA12CA1 | |
| Hydrochloric Acid SCHEMBL8166998 | 0.79 | MEN1 (0.51) | GRK2USP2 | |
| SCHEMBL9779996 | 0.79 | MAPT (0.56) | GRK2 | |
| SCHEMBL6904254 | 0.79 | ALDH1A1 (0.51) | CA12CA1CA2CA9EGFR | |
| SCHEMBL8021371 | 0.79 | SAE1 (0.51) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL9780049 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BGRK2USP2 | |
| SCHEMBL1733736 | 0.78 | GRK2 (0.47) | MTNR1AMTNR1BCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |