Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795576 | 0.82 | ALOX5 (0.54) | ALOX5MGLLALDH1A1 | |
| SCHEMBL9795754 | 0.82 | ALOX5 (0.54) | ALOX5MGLLMAPTPKM | |
| SCHEMBL9795544 | 0.82 | ALOX5 (0.56) | ALOX5ALDH1A1MAPTGAA | |
| SCHEMBL9795578 | 0.82 | MMP13 (0.40) | ALOX5MGLLGAA | |
| SCHEMBL9795696 | 0.81 | BPTF (0.35) | ALOX5ALDH1A1DDB1CRBN | |
| SCHEMBL9795564 | 0.80 | ALOX5 (0.56) | ALOX5MGLLALDH1A1MAPTGAA | |
| SCHEMBL9795810 | 0.78 | MGLL (0.42) | ALOX5MGLLALDH1A1CYP2C19TDP1 | |
| SCHEMBL9795750 | 0.78 | ALOX5 (0.35) | ALOX5MAPTPKMGSK3BBACE1 | |
| SCHEMBL9795636 | 0.76 | MMP2 (0.46) | ALOX5MGLL | |
| SCHEMBL9795652 | 0.75 | ADRB1 (0.40) | ALOX5ALDH1A1MAPTCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | claimed |
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |