Sugi Predict

Sugi Predict / Compounds / SCHEMBL214546

SCHEMBL214546

SCHEMBL214546

CC(O)Oc1cc(N)ccc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 0.42
▸ GAA P10253 4/20 0.42
▸ MAPT P10636 5/20 0.37
▸ TSHR P16473 4/20 0.37
▸ HTT P42858 2/20 0.37
▸ MAPK1 P28482 2/20 0.37
▸ CYP3A4 P08684 4/20 0.36
▸ TDP1 Q9NUW8 3/20 0.36
▸ HSD17B10 Q99714 3/20 0.36
▸ CASP1 P29466 4/20 0.35
▸ ALOX5 P09917 1/20 0.35
▸ MEN1 O00255 3/20 0.34
▸ POLB P06746 3/20 0.34
▸ KMT2A Q03164 3/20 0.34
▸ USP2 O75604 2/20 0.34
▸ ALOX15 P16050 2/20 0.34
▸ THRB P10828 2/20 0.34
▸ RECQL P46063 2/20 0.34
▸ PKM P14618 1/20 0.34
▸ APEX1 P27695 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5792316 0.98 ALDH1A1 (0.44) ALDH1A1GAAMAPTTSHRHTT
SCHEMBL111528 0.85 ALDH1A1 (0.40) ALDH1A1GAAMAPTTSHRHTT
SCHEMBL7076235 0.84 PDE10A (0.47) ALDH1A1GAAMAPTTSHRHTT
SCHEMBL129715 0.84 ALDH1A1 (0.46) ALDH1A1GAAMAPTTSHRHTT
SCHEMBL128535 0.84 PDE10A (0.47) ALDH1A1GAAMAPTTSHRHTT
SCHEMBL7519140 0.83 ALDH1A1 (0.44) ALDH1A1GAAMAPTTSHRHTT
Hydrochloric Acid SCHEMBL10397659 0.82 ALDH1A1 (0.49) ALDH1A1GAAMAPTTSHRHTT
SCHEMBL11691601 0.82 CASP1 (0.45) ALDH1A1GAAMAPTTSHRHTT
Hydrochloric Acid SCHEMBL29836005 0.82 ALDH1A1 (0.49) ALDH1A1GAAMAPTTSHRHTT
SCHEMBL9795689 0.82 MAOB (0.39) ALDH1A1GAAMAPTTSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3464247-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'Oréal (FR) 2019-04-10 — — EP claimed
WO-2017202884-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2017-11-30 — — WO claimed
US-6692537-B1 ENZYME OF 2-ELECTRON OXIDOREDUCTASE TYPE IN THE PRESENCE OF AT LEAST ONE DONOR FOR THE SAID ENZYME AND AT LEAST ONE NONIONIC FATTY SUCRONAMIDE L'OREAL S.A. (FR) 2004-02-17 — — US claimed
EP-1367983-A1 MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS L'OREAL (FR) 2003-12-10 — — EP claimed
EP-1332126-A1 NOVEL COUPLING COMPONENTS FOR OXIDATION DYES Henkel Kommanditgesellschaft auf Aktien (DE) 2003-08-06 — — EP claimed
EP-1301496-A2 NOVEL COUPLING COMPONENTS FOR OXIDATION COLOURING AGENTS Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-16 — — EP claimed
US-20020170122-A9 Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods L'OREAL S.A. (FR) 2002-11-21 — — US claimed
WO-2002069922-A1 MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS L'OREAL (FR) 2002-09-12 — — WO claimed
WO-2002038533-A1 NOVEL COUPLING COMPONENTS FOR OXIDATION DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-05-16 — — WO claimed
WO-2002006207-A2 NOVEL COUPLING COMPONENTS FOR OXIDATION COLOURING AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-01-24 — — WO claimed
US-4985042-A New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1991-01-15 — — US claimed
US-4954131-A Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1990-09-04 — — US claimed
US-4863480-A OXIDATION COLOR DYES THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) 1989-09-05 — — US claimed
WO-2025069042-A1 COMPOSITIONS AND METHODS FOR DYEING AND/OR LIGHTENING KERATIN FIBRES L'OREAL (FR) 2025-04-03 — — WO disclosed
EP-4395734-A1 COMPOSITIONS, KITS, AND METHODS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2024-07-10 — — EP disclosed
WO-2024134667-A1 A DEVICE COMPRISING OXIDATIVE COMPOSITION FOR DYEING OF KERATIN FIBRES L'OREAL (FR) 2024-06-27 — — WO disclosed
US-4314810-A Compositions suitable for use in dyeing hair obtained from the reaction of a polyhydroxybenzene and an oxidative dyestuff precursor of the para type L'OREAL (FR) 1982-02-09 — — US disclosed
US-4311478-A HAIR DYES L'OREAL (FR) 1982-01-19 — — US disclosed
US-4289495-A HAIR DYES, STORAGE STABILITY L'OREAL (FR) 1981-09-15 — — US disclosed
US-4152112-A Dyeing composition for keratinic fibers containing paraphenylenediamines L'OREAL (FR) 1979-05-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020170122-A9 Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods KRT18, PPOX, AOX1 ALDH1A1 104/4885GAA 1324/4885MAPT 856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.