Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795938 | 0.81 | VCAM1 (0.66) | VCAM1ALDH1A1MAPTCA12CA1 | |
| SCHEMBL8572889 | 0.81 | VCAM1 (0.66) | VCAM1ALDH1A1MAPTCA12CA1 | |
| SCHEMBL994159 | 0.80 | ALDH1A1 (0.69) | VCAM1ALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL27973770 | 0.78 | MCOLN3 (0.55) | ALDH1A1MAPTTDP1HTTL3MBTL1 | |
| SCHEMBL11442100 | 0.77 | VCAM1 (0.61) | VCAM1ALDH1A1HTTCRHBPCRHR2 | |
| SCHEMBL1368775 | 0.77 | L3MBTL1 (0.51) | VCAM1ALDH1A1CA12CA1CA9 | |
| SCHEMBL28031906 | 0.76 | CA12 (0.69) | VCAM1ALDH1A1MAPTCA12CA1 | |
| SCHEMBL10468337 | 0.76 | VCAM1 (1.00) | VCAM1ALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL9796235 | 0.75 | VCAM1 (0.56) | VCAM1ALDH1A1MAPTCA12CA1 | |
| SCHEMBL5469177 | 0.75 | PKM (0.62) | VCAM1ALDH1A1MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990523-A | Treatment of chronic inflammatory joint disease with arylsulfonamides | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-02-05 | — | — | US | disclosed |
| WO-1990015600-A2 | TREATMENT OF CHRONIC INFLAMMATORY JOINT DISEASE WITH ARYLSULFONAMIDES | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-27 | — | — | WO | disclosed |