Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043409 | 0.95 | UTS2R (0.42) | UTS2RHRH3SIGMAR1PTGESALOX5 | |
| SCHEMBL16673003 | 0.90 | UTS2R (0.45) | UTS2RSIGMAR1ALOX5ACHELMNA | |
| SCHEMBL6666615 | 0.85 | PABPC1 (0.50) | PPARGPPARAPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL9795863 | 0.83 | SIGMAR1 (0.39) | SIGMAR1PPARGPPARAPABPC1APOBEC3A | |
| SCHEMBL9796059 | 0.82 | PSEN1 (0.42) | ALOX5PPARGPPARALMNAKMT2A | |
| SCHEMBL23664923 | 0.79 | ALDH1A1 (0.49) | PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL27477569 | 0.79 | ALDH1A1 (0.49) | PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL9340624 | 0.79 | ALDH1A1 (0.49) | PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL8750434 | 0.79 | HRH3 (0.44) | UTS2RHRH3PTGESALOX5PPARG | |
| SCHEMBL5046764 | 0.79 | LTA4H (0.38) | SIGMAR1PABPC1APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006534-A | Substituted ethers, thioethers and amines for use as lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |