Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485774 | 0.87 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1KMT2AMEN1 | |
| Methylene Chloride SCHEMBL6230558 | 0.83 | CA2 (0.40) | ALDH1A1HSD17B10TDP1CA12CYP1A2 | |
| Toluene SCHEMBL18394201 | 0.83 | LMNA (0.46) | ALDH1A1HSD17B10TDP1ACHECYP1A2 | |
| Toluene SCHEMBL1393755 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL11583152 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TDP1CA12CA9 | |
| Toluene SCHEMBL27723212 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TDP1KMT2AMEN1 | |
| SCHEMBL840528 | 0.77 | CYP1A2 (0.50) | ALDH1A1TDP1KMT2AMEN1ACHE | |
| Toluene SCHEMBL7520597 | 0.77 | ALDH1A1 (0.76) | ALDH1A1HSD17B10TDP1ACHECA12 | |
| SCHEMBL8319815 | 0.76 | CA2 (0.40) | ALDH1A1HSD17B10TDP1CNR2KMT2A | |
| SCHEMBL9510374 | 0.76 | CA2 (0.40) | ALDH1A1HSD17B10TDP1CNR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250213-B1 | SILSESQUIOXANE RESINS | DOW CORNING (US) | 2013-08-21 | — | — | EP | disclosed |
| US-8304161-B2 | Silsesquioxane resins | DOW CORNING CORPORATION (US) | 2012-11-06 | — | — | US | disclosed |
| US-20110003249-A1 | Silsesquioxane Resins | DOW CORNING CORPORATION | 2011-01-06 | — | — | US | disclosed |
| EP-2250213-A2 | SILSESQUIOXANE RESINS | Dow Corning Corporation (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009111122-A2 | SILSESQUIOXANE RESINS | DOW CORNING CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |