SCHEMBL979737

SCHEMBL979737

COc1cccc(OC(=O)O)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.57
MAPT P10636 3/20 0.57
LMNA P02545 3/20 0.57
ALOX15 P16050 2/20 0.57
MAPK1 P28482 2/20 0.57
HSD17B10 Q99714 2/20 0.57
TP53 P04637 2/20 0.57
ALDH1A1 P00352 1/20 0.57
CYP3A4 P08684 1/20 0.57
HPGD P15428 1/20 0.57
ALOX12 P18054 1/20 0.57
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA12 O43570 3/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
TLR2 O60603 1/20 0.52
ERN1 O75460 1/20 0.52
TLR1 Q15399 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8013103 0.89 CA12 (0.41) KDM4EMAPTLMNAALOX15MAPK1
SCHEMBL2878372 0.84 KDM4E (0.57) KDM4EMAPTLMNAALOX15MAPK1
Syringol SCHEMBL156388 0.82 KDM4E (0.80) KDM4EMAPTLMNAALOX15MAPK1
SCHEMBL3373821 0.82 LMNA (0.55) KDM4EMAPTLMNAALOX15MAPK1
SCHEMBL1462600 0.81 HSD17B10 (0.52) KDM4EMAPTLMNAALOX15MAPK1
SCHEMBL21540 0.81 CA1 (0.59) MAPTLMNAMAPK1TP53ALDH1A1
Syringol SCHEMBL28128050 0.81 KDM4E (0.70) KDM4EMAPTLMNAALOX15MAPK1
Syringol SCHEMBL6049240 0.80 KDM4E (0.76) KDM4EMAPTLMNAALOX15MAPK1
Syringol SCHEMBL7610366 0.80 KDM4E (0.76) KDM4EMAPTLMNAALOX15MAPK1
Syringol SCHEMBL8986496 0.80 KDM4E (0.76) KDM4EMAPTLMNAALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7871953-B2 Late transition metal catalysts for olefin oligomerizations EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-01-18 US disclosed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
US-20050003955-A1 Late transition metal catalysts for olefin oligomerizations EXXONMOBIL CHEMICAL PATENTS INC. 2005-01-06 US disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 KDM4E 1868/4885MAPT 585/4885LMNA 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.