SCHEMBL8013103

SCHEMBL8013103

O=C(O)Oc1cccc(OC(=O)O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
SERPINE1 P05121 1/20 0.41
HSD17B10 Q99714 7/20 0.40
MAPT P10636 4/20 0.40
KMT2A Q03164 3/20 0.40
ESR1 P03372 3/20 0.40
ALOX15 P16050 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
GAA P10253 2/20 0.40
ESR2 Q92731 2/20 0.40
MEN1 O00255 1/20 0.40
JAK2 O60674 1/20 0.40
USP2 O75604 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KDM4E B2RXH2 6/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1462600 0.91 HSD17B10 (0.52) CA12CA1CA2CA7CA9
SCHEMBL979737 0.89 KDM4E (0.57) CA12CA1CA2CA7CA9
SCHEMBL5682698 0.89 HNF4A (0.38) CA12CA1CA2CA7CA9
SCHEMBL5588539 0.85 ALDH1A1 (0.52) CA12CA1CA2CA7CA9
SCHEMBL5193492 0.82 GABRA1 (0.57) CA12CA1CA2CA7CA9
SCHEMBL5590483 0.82 HNF4A (0.55) HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1
SCHEMBL143632 0.81 KDM4E (0.46) CA12CA1CA2CA7CA9
SCHEMBL5590668 0.80 CYP2D6 (0.34) CA12CA1CA2CA7CA9
SCHEMBL5589142 0.80 CYP2D6 (0.34) CA12CA1CA2CA7CA9
SCHEMBL5587910 0.80 GAA (0.38) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0968310-A1 NOVEL PHENOL CONDENSATION PRODUCTS Bayer Aktiengesellschaft (DE) 2000-01-05 EP disclosed
WO-1998042877-A1 NOVEL PHENOL CONDENSATION PRODUCTS BAYER AKTIENGESELLSCHAFT (DE) 1998-10-01 WO disclosed