Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244773 | 0.88 | ALDH1A1 (0.45) | MAPK1KMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL17256401 | 0.83 | TEAD3 (0.43) | MAPK1KMT2AHPGDALDH1A1PKM | |
| SCHEMBL2450503 | 0.82 | KMT2A (0.57) | MAPK1KMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL17256395 | 0.81 | EPHX2 (0.48) | ALDH1A1FAAHL3MBTL1 | |
| SCHEMBL23191944 | 0.81 | ALDH1A1 (0.50) | MAPK1KMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL15450611 | 0.81 | NOTUM (0.52) | MAPK1KMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL2568708 | 0.80 | ADORA3 (0.37) | MGLL | |
| SCHEMBL4399193 | 0.80 | PARL (0.38) | MAPK1KMT2AHPGDALDH1A1PKM | |
| SCHEMBL406279 | 0.78 | KMT2A (0.41) | GRM5MAPK1KMT2ATSHRALDH1A1 | |
| SCHEMBL16620495 | 0.78 | ALDH1A1 (0.47) | MAPK1KMT2AALDH1A1MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222172-B1 | N-GLYCOLYLNEURAMINIC ACID DERIVATIVE | MECT CORPORATION (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4774327-A | N-glycolylneuraminic acid derivative | MECT CORPORATION (JP) | 1988-09-27 | — | — | US | disclosed |
| EP-0222172-A2 | N-Glycolylneuraminic acid derivative | MECT CORPORATION (JP) | 1987-05-20 | — | — | EP | disclosed |