Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9797851 | 0.92 | OPRL1 (0.52) | OPRL1OPRM1OPRD1OPRK1S1PR1 | |
| SCHEMBL9797932 | 0.90 | S1PR3 (0.53) | OPRL1OPRM1OPRD1OPRK1S1PR1 | |
| SCHEMBL9798829 | 0.89 | S1PR3 (0.55) | OPRL1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9797674 | 0.89 | S1PR3 (0.55) | OPRL1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9798111 | 0.89 | S1PR3 (0.55) | OPRL1S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9797993 | 0.88 | ALDH1A1 (0.49) | OPRL1OPRM1OPRD1OPRK1S1PR1 | |
| SCHEMBL9810262 | 0.85 | OPRL1 (0.44) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL9810389 | 0.83 | OPRM1 (0.43) | OPRL1OPRM1OPRD1OPRK1L3MBTL1 | |
| SCHEMBL11077672 | 0.83 | OPRL1 (0.52) | OPRL1OPRM1OPRD1OPRK1PLK1 | |
| SCHEMBL9810386 | 0.82 | OPRL1 (0.43) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261160-B1 | ALICYCLIC COMPOUNDS | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |