Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810484 | 0.92 | THRA (0.49) | OPRL1OPRM1OPRD1OPRK1THRA | |
| SCHEMBL9810674 | 0.91 | THRA (0.54) | OPRL1THRATHRBSLC6A3ALDH1A1 | |
| SCHEMBL9810264 | 0.90 | THRA (0.55) | OPRL1THRATHRB | |
| SCHEMBL9810306 | 0.90 | THRA (0.55) | OPRL1THRATHRB | |
| SCHEMBL9810418 | 0.90 | THRA (0.55) | OPRL1THRATHRB | |
| SCHEMBL9810441 | 0.89 | ALDH1A1 (0.46) | OPRL1OPRM1OPRD1OPRK1SLC6A3 | |
| SCHEMBL9810389 | 0.88 | OPRM1 (0.43) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL9810386 | 0.87 | OPRL1 (0.43) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL9810669 | 0.85 | OPRL1 (0.41) | OPRL1OPRM1OPRD1OPRK1THRA | |
| SCHEMBL9798019 | 0.85 | OPRL1 (0.50) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068389-A | TERTIARY ALCOHOLS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |