Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798019 | 0.88 | OPRL1 (0.50) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9797851 | 0.85 | OPRL1 (0.52) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9797932 | 0.84 | S1PR3 (0.53) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9810441 | 0.84 | ALDH1A1 (0.46) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9797674 | 0.83 | S1PR3 (0.55) | ALDH1A1OPRL1S1PR1S1PR5MEN1 | |
| SCHEMBL9798111 | 0.83 | S1PR3 (0.55) | ALDH1A1OPRL1S1PR1S1PR5MEN1 | |
| SCHEMBL9798829 | 0.83 | S1PR3 (0.55) | ALDH1A1OPRL1S1PR1S1PR5MEN1 | |
| SCHEMBL9810410 | 0.82 | LMNA (0.53) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9797999 | 0.81 | OPRM1 (0.45) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9798815 | 0.81 | KMT2A (0.43) | ALDH1A1S1PR5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261160-B1 | ALICYCLIC COMPOUNDS | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |