Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212791 | 0.89 | CYP1A2 (0.39) | ALDH1A1CYP3A4SMN1; SMN2TP53TSHR | |
| SCHEMBL9743680 | 0.87 | CYP1A2 (0.38) | ALDH1A1CYP3A4TSHRPOLBCYP1A2 | |
| SCHEMBL10637836 | 0.86 | HRH3 (0.39) | ALDH1A1POLBNPSR1KDM4EGAA | |
| SCHEMBL10501329 | 0.84 | CYP1A2 (0.37) | CYP3A4POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9638630 | 0.83 | ALDH1A1 (0.42) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL4890255 | 0.81 | L3MBTL1 (0.50) | ALDH1A1CYP3A4SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL9650616 | 0.81 | POLB (0.44) | ALDH1A1SMN1; SMN2TP53POLBCYP1A2 | |
| SCHEMBL8645132 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL10501291 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 | |
| SCHEMBL7779660 | 0.79 | TSHR (0.47) | ALDH1A1CYP3A4SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240320-B1 | PHENYLPYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1991-02-27 | — | — | EP | disclosed |
| EP-0194153-B1 | PYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0160790-B1 | BIPYRIMIDINYL DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Chisso Corporation (JP) | 1989-08-16 | — | — | EP | disclosed |
| EP-0205340-B1 | LIQUID CRYSTAL ESTER COMPOUND | Chisso Corporation (JP) | 1989-01-11 | — | — | EP | disclosed |
| US-4772416-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0151294-B1 | 2-SUBSTITUTED-6-(5-SUBSTITUTED-2-PYRIMIDINYL)NAPHTHALENES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | Chisso Corporation (JP) | 1988-06-22 | — | — | EP | disclosed |
| EP-0240320-A2 | Phenylpyridine derivatives | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4684477-A | LOW VISCOSITY, LOW VOLTAGE | CHISSO CORPORATION (JP) | 1987-08-04 | — | — | US | disclosed |
| US-4680137-A | Liquid crystal ester compound | CHISSO CORPORATION (JP) | 1987-07-14 | — | — | US | disclosed |
| US-4659500-A | Ester derivative having a positive dielectric anisotropy | CHISSO CORPORATION (JP) | 1987-04-21 | — | — | US | disclosed |
| US-4642199-A | Novel liquid crystal compounds and liquid crystal compositions containing same | CHISSO CORPORATION (JP) | 1987-02-10 | — | — | US | disclosed |
| EP-0205340-A1 | Liquid crystal ester compound | Chisso Corporation (JP) | 1986-12-17 | — | — | EP | disclosed |
| EP-0194153-A2 | Pyridine derivatives | Chisso Corporation (JP) | 1986-09-10 | — | — | EP | disclosed |
| US-4609485-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1986-09-02 | — | — | US | disclosed |
| US-4585575-A | LIQUID CRYSTALS HAVING LARGE VALUE OF OPTICAL ANISOTROPY | CHISSO CORPORATION (JP) | 1986-04-29 | — | — | US | disclosed |
| US-4576733-A | 4-Halogenobenzoic acid esters | CHISSO CORPORATION (JP) | 1986-03-18 | — | — | US | disclosed |
| EP-0164721-A2 | Novel liquid crystal compound and liquid crystal composition containing same | Chisso Corporation (JP) | 1985-12-18 | — | — | EP | disclosed |
| EP-0160790-A2 | Bipyrimidinyl derivatives and liquid crystal compositions containing them | Chisso Corporation (JP) | 1985-11-13 | — | — | EP | disclosed |
| EP-0151294-A1 | 2-Substituted-6-(5-substituted-2-pyrimidinyl)naphthalenes and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1985-08-14 | — | — | EP | disclosed |