Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586609 | 0.91 | CYP11B1 (0.48) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9637460 | 0.91 | CYP11B1 (0.53) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9805327 | 0.82 | CYP11B1 (0.51) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9021665 | 0.82 | KDM4E (0.61) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9798121 | 0.81 | ALDH1A1 (0.36) | L3MBTL1KDM4EALDH1A1HPGDCYP11B1 | |
| SCHEMBL9805468 | 0.80 | CYP11B1 (0.49) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL7779660 | 0.80 | TSHR (0.47) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL2352483 | 0.80 | TSHR (0.47) | ALDH1A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL13986853 | 0.80 | KDM4E (0.59) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL29818872 | 0.80 | KDM4E (0.54) | L3MBTL1KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465802-B2 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | FU JEN CATHOLIC UNIVERSITY (TW) | 2008-12-16 | — | — | US | claimed |
| US-20080146813-A1 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | FU JEN CATHOLIC UNIVERSITY (TW) | 2008-06-19 | — | — | US | claimed |
| US-20190181356-A1 | ORGANOMETALLIC IRIDIUM COMPLEX, SYNTHETIC METHOD THEREOF, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | FU JEN CATHOLIC UNIVERSITY (TW) | 2019-06-13 | — | — | US | disclosed |
| US-7465802-B2 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | FU JEN CATHOLIC UNIVERSITY (TW) | 2008-12-16 | — | — | US | disclosed |
| US-7465802-B2 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | FU JEN CATHOLIC UNIVERSITY (TW) | 2008-12-16 | — | — | US | disclosed |
| US-7465802-B2 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | FU JEN CATHOLIC UNIVERSITY (TW) | 2008-12-16 | — | — | US | disclosed |
| US-20080146813-A1 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | FU JEN CATHOLIC UNIVERSITY (TW) | 2008-06-19 | — | — | US | disclosed |
| US-20080146813-A1 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | FU JEN CATHOLIC UNIVERSITY (TW) | 2008-06-19 | — | — | US | disclosed |
| US-20080146813-A1 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | FU JEN CATHOLIC UNIVERSITY (TW) | 2008-06-19 | — | — | US | disclosed |
| EP-0310676-A1 | LIQUID-CRYSTAL DERIVATIVES OF 2,5-DISUBSTITUTED PYRIDINE AS COMPONENTS OF LIQUID-CRYSTAL MATERIAL, AND A LIQUID-CRYSTAL MATERIAL | PAVLJUCHENKO, Assya Iosifovna (RU) | 1989-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146813-A1 | Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine which is oxidized with o-chloronil to obtain the 2-(4'-alkylphenyl)-5-cyanopyridine; display system | CBR3, OCIAD2, OCIAD1 | L3MBTL1 2373/4885KDM4E 1622/4885ALDH1A1 1257/4885 |
| US-20190181356-A1 | ORGANOMETALLIC IRIDIUM COMPLEX, SYNTHETIC METHOD THEREOF, AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME | TST, AOX1, HAT1 | L3MBTL1 1352/4885KDM4E 4754/4885ALDH1A1 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.