Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 9/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799057 | 1.00 | PLA2G2A (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5SOAT1 | |
| SCHEMBL9529973 | 0.84 | SOAT1 (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5SOAT1 | |
| SCHEMBL9529975 | 0.84 | SOAT1 (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5SOAT1 | |
| SCHEMBL9798365 | 0.81 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9799022 | 0.81 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9798948 | 0.81 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9798355 | 0.81 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9798498 | 0.78 | PLA2G2C (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5HDAC3 | |
| SCHEMBL2233937 | 0.77 | PLA2G2A (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9527629 | 0.76 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |