Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700873 | 0.90 | PRKD3 (0.48) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL8917115 | 0.90 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL497520 | 0.90 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL9137670 | 0.90 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8638519 | 0.90 | PRKD3 (0.48) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL8979451 | 0.89 | PLA2G2A (0.54) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL25763996 | 0.85 | PLA2G2A (0.48) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8357825 | 0.85 | PLA2G2A (0.59) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL25243275 | 0.84 | USP2 (0.50) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL10706918 | 0.84 | PLA2G2A (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207703-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | VASCULAR BIOGENICS LTD. (IL) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207703-A1 | OXIDIZED LIPID COMPOUNDS AND USES THEREOF | LPO, GPX4, ALOX15B | PLA2G2A 343/4885PLA2G10 397/4885PLA2G1B 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.