Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907784 | 0.85 | PTGS2 (0.37) | CYP11B1CYP11B2PTGS2GPR84MAOB | |
| SCHEMBL9797964 | 0.83 | CYP11B1 (0.39) | CYP11B1CYP11B2CYP19A1PTGS2KDM1A | |
| SCHEMBL11025756 | 0.74 | KDM1A (0.46) | CYP11B1CYP11B2CYP19A1PTGS2KDM1A | |
| SCHEMBL12797023 | 0.73 | TSHR (0.35) | CYP11B1CYP11B2CYP19A1PTGS2KDM1A | |
| SCHEMBL8569166 | 0.73 | PTGS2 (0.49) | CYP11B1CYP11B2CYP19A1PTGS2KDM1A | |
| SCHEMBL30661162 | 0.73 | PTGS2 (0.49) | CYP11B1CYP11B2CYP19A1PTGS2KDM1A | |
| SCHEMBL268878 | 0.73 | CA12 (0.40) | CYP11B1CYP11B2CYP19A1MAOBHSP90AA1 | |
| SCHEMBL28840682 | 0.71 | ELANE (0.42) | PTGS2KDM1AGPR84MAOB | |
| SCHEMBL6908479 | 0.69 | PTGS2 (0.33) | CYP11B1CYP11B2PTGS2 | |
| SCHEMBL7423243 | 0.67 | PTGS2 (0.41) | CYP11B1CYP11B2CYP19A1PTGS2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992591-A | Preparation of alpha-(3,4-disubstituted aryl) cyclic ketones | SCHERING CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |