Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798491 | 0.83 | MEN1 (0.39) | ELANEMEN1KMT2ALMNAMAPT | |
| SCHEMBL30661164 | 0.83 | MEN1 (0.39) | ELANEMEN1KMT2ALMNAMAPT | |
| SCHEMBL13211923 | 0.78 | ELANE (0.41) | ELANEMEN1KMT2AGPR84PTGS2 | |
| SCHEMBL12831509 | 0.76 | GPR84 (0.35) | GPR84PTGS2MAOAMAOBKDM1A | |
| SCHEMBL29082480 | 0.75 | ALOX5 (0.48) | ELANEMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL11025756 | 0.74 | KDM1A (0.46) | GPR84PTGS2MAOBKDM1A | |
| SCHEMBL31274601 | 0.74 | ELANE (0.41) | ELANEMEN1KMT2A | |
| SCHEMBL8569166 | 0.73 | PTGS2 (0.49) | GPR84PTGS2MAOBKDM1A | |
| SCHEMBL30661162 | 0.73 | PTGS2 (0.49) | GPR84PTGS2MAOBKDM1A | |
| SCHEMBL9797964 | 0.73 | CYP11B1 (0.39) | GPR84PTGS2MAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907404-B | 5- (2- (Disubstituted phosphino) phenyl) -1-alkyl-1H-pyrazolyl phosphine ligand and preparation method and application thereof | 香港理工大学深圳研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-114907404-A | 5- (2- (disubstituted phosphino) phenyl) -1-alkyl-1H-pyrazolylphosphine ligand and preparation method and application thereof | 香港理工大学深圳研究院 | 2022-08-16 | — | — | CN | disclosed |