SCHEMBL9799149

SCHEMBL9799149

[CH2]CNC(=O)N1CCCCO1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.31
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29433552 0.76 CTSK (0.41) HTT
SCHEMBL5522397 0.71 KMT2A (0.48) HTT
SCHEMBL16611870 0.71
SCHEMBL28944683 0.71 TRPM8 (0.39) TRPM8
SCHEMBL7955691 0.70
SCHEMBL5524889 0.70 KMT2A (0.46) HTT
SCHEMBL21952207 0.69
SCHEMBL3169784 0.68
SCHEMBL7292726 0.67 RAB9A (0.36) TRPM8
SCHEMBL8431500 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0229947-B1 NOVEL CRYSTALLINE SALTS OF ARYLOXY-PROPANOLAMINES, THEIR PREPARATION AND THEIR USE RORER INTERNATIONAL (OVERSEAS) INC. (US) 1991-03-13 EP disclosed
US-4849530-A Process for the preparation of crystalline salts or aryloxy-propanolamines RORER PHARMACEUTICAL CORPORATION (US) 1989-07-18 US disclosed
US-4767784-A DIPHENYLACETATES RORER PHARMACEUTICAL CORPORATION 1988-08-30 US disclosed