Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801844 | 0.89 | SIRT2 (0.56) | RAB9AKMT2AKDM1AMAOB | |
| SCHEMBL11360828 | 0.89 | LMNA (0.62) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10807106 | 0.87 | NR1H4 (0.57) | RAB9AKMT2ASMN1; SMN2KDM1AMAOB | |
| SCHEMBL10806965 | 0.86 | PDK1 (0.61) | NPC1RAB9AMEN1KMT2AMAOB | |
| SCHEMBL11356870 | 0.86 | THRB (0.52) | MEN1KMT2AKDM1AMAOBTHRB | |
| SCHEMBL11425817 | 0.84 | MTNR1A (0.51) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11198895 | 0.84 | HTT (0.53) | KDM1AMAOBTHRB | |
| SCHEMBL11133791 | 0.82 | NPY5R (0.55) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10805203 | 0.82 | SIRT2 (0.58) | SMN1; SMN2THRBALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11630497 | 0.81 | SMN1; SMN2 (0.50) | RAB9AMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015762-A | Alkoxy substituted ureas as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4422871-A | Aralkylphenylureas and herbicides containing these | BASF AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |