SCHEMBL9799303

SCHEMBL9799303

C=C(CC(C)(C)c1ccccc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.50
HIF1A Q16665 1/20 0.50
TET2 Q6N021 1/20 0.47
ME2 P23368 2/20 0.46
ME1 P48163 2/20 0.46
ME3 Q16798 2/20 0.46
ALDH1A1 P00352 4/20 0.45
HTT P42858 2/20 0.45
TAAR1 Q96RJ0 1/20 0.45
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8609279 0.83 TET2 (0.43) CYP2C19HIF1ATET2ME2ME1
SCHEMBL5884800 0.82 ALDH1A1 (0.44) CYP2C19HIF1AME2ME1ME3
SCHEMBL7739108 0.82 CYP2C19 (0.61) CYP2C19HIF1AME2ME1ME3
SCHEMBL14995437 0.81 CYP2C19 (0.47) CYP2C19HIF1ATET2ALDH1A1HTT
SCHEMBL3535049 0.80 CYP2C19 (0.53) CYP2C19HIF1AME2ME1ME3
SCHEMBL11124539 0.80 CYP2C19 (0.44) CYP2C19HIF1ATET2ALDH1A1HTT
SCHEMBL5884983 0.80 MAPT (0.50) CYP2C19HIF1AME2ME1ME3
SCHEMBL57411 0.79 CYP2C19 (0.69) CYP2C19HIF1AME2ME1ME3
SCHEMBL1404274 0.79 CYP2C19 (0.48) CYP2C19HIF1AME2ME1ME3
SCHEMBL28864314 0.78 TAAR1 (0.50) CYP2C19HIF1AME2ME1ME3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0158357-B1 METHOD OF FORMING RESIST MICROPATTERN NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-02-27 EP claimed
US-4634645-A FORMING RECESSED PATTERN WITH ENERGY BEAM NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1987-01-06 US claimed
US-9557642-B2 Photoresist composition and associated method of forming an electronic device ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2017-01-31 US disclosed
US-9499513-B2 Acid generators and photoresists comprising same ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2016-11-22 US disclosed
US-20160103392-A1 PHOTORESIST COMPOSITION AND ASSOCIATED METHOD OF FORMING AN ELECTRONIC DEVICE U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-04-14 US disclosed
US-20160002199-A1 ACID GENERATORS AND PHOTORESISTS COMPRISING SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-01-07 US disclosed
EP-0158357-B1 METHOD OF FORMING RESIST MICROPATTERN NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-02-27 EP disclosed
US-4634645-A FORMING RECESSED PATTERN WITH ENERGY BEAM NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1987-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002199-A1 ACID GENERATORS AND PHOTORESISTS COMPRISING SAME MPST, PSAT1, TST CYP2C19 1298/4885HIF1A 819/4885TET2 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.