Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799632 | 0.90 | FEN1 (0.50) | ALDH1A1LMNAKDM4EGLAGAA | |
| SCHEMBL9799505 | 0.77 | MEN1 (0.47) | ALDH1A1KDM4EGAAMAPTPDE4A | |
| SCHEMBL9799506 | 0.76 | PDE4A (0.54) | ALDH1A1KDM4EMAPTPDE4APDE4B | |
| SCHEMBL9799533 | 0.76 | FEN1 (0.50) | ALDH1A1LMNAPDE4APDE4BPDE4C | |
| SCHEMBL9628888 | 0.75 | PKM (0.47) | ALDH1A1LMNAPKMMAPTPDE4A | |
| SCHEMBL10378764 | 0.75 | KAT2B (0.48) | ALDH1A1LMNAPKMMAPTPDE4A | |
| SCHEMBL9799507 | 0.74 | PDE4A (0.50) | ALDH1A1LMNAKDM4ENPC1MAPT | |
| SCHEMBL9629703 | 0.74 | PKM (0.45) | ALDH1A1LMNAPKMMAPTPDE4B | |
| SCHEMBL8803998 | 0.72 | KMT2A (0.54) | ALDH1A1LMNAPKMMAPTPDE4A | |
| SCHEMBL10379024 | 0.72 | PKM (0.45) | ALDH1A1LMNAKDM4EPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996212-A | Antiinflammatory and anti-hyperproliferative compounds | SCHERING CORPORATION (US) | 1991-02-26 | — | — | US | claimed |
| US-4859669-A | Antiinflammatory and anti-hyperproliferative naphthyridin-4-ones | SCHERING CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |