Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18885212 | 0.77 | RECQL (0.46) | RECQLALDH1A1 | |
| SCHEMBL12270200 | 0.77 | KDM4E (0.32) | ATMRECQLALDH1A1 | |
| SCHEMBL5272522 | 0.74 | BIRC5 (0.46) | ATMALDH1A1 | |
| SCHEMBL7802726 | 0.74 | FAAH (0.34) | ATMRECQLALDH1A1 | |
| SCHEMBL14940069 | 0.71 | — | — | |
| SCHEMBL4584394 | 0.71 | LMNA (0.45) | RECQLALDH1A1 | |
| SCHEMBL2531715 | 0.70 | ALDH1A1 (0.38) | ATMALDH1A1 | |
| SCHEMBL1639520 | 0.67 | MAPT (0.48) | RECQLALDH1A1 | |
| SCHEMBL8137135 | 0.67 | KEAP1 (0.49) | ALDH1A1 | |
| SCHEMBL196349 | 0.67 | ALDH1A1 (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039904-B | Is suitable for treating dopamine D3Heterocyclic compounds for receptor-modulated responsive disorders | ABBOTT GMBH & CO KG | 2014-09-24 | — | — | CN | disclosed |
| US-4990621-A | Insecticides, miticides and nematocides; 3-(3-fluoro-4-phenoxyphenyl, 3-(5-fluoro-3-phenoxypyrid-2-yl) or 3-(3-methyl-4-phenyl prop-1-ene | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |