Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.62 |
| ▸ | JAK2 | O60674 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | GPX4 | P36969 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517681 | 0.98 | NR1I2 (0.67) | NR1I2TDP1MEN1KMT2ATP53 | |
| SCHEMBL7274382 | 0.85 | ALDH1A1 (0.70) | NR1I2TDP1MEN1KMT2ATP53 | |
| SCHEMBL8734929 | 0.85 | NR1I2 (0.85) | NR1I2TDP1MEN1KMT2ATP53 | |
| SCHEMBL9614029 | 0.82 | TP53 (0.71) | NR1I2TDP1MEN1KMT2ATP53 | |
| Pretilachlor SCHEMBL63720 | 0.81 | NR1I2 (1.00) | NR1I2TDP1MEN1KMT2ATP53 | |
| Pretilachlor SCHEMBL7932522 | 0.81 | NR1I2 (1.00) | NR1I2TDP1MEN1KMT2ATP53 | |
| Alachlor SCHEMBL27741703 | 0.81 | TP53 (0.82) | NR1I2TDP1MEN1KMT2ATP53 | |
| SCHEMBL27976189 | 0.81 | TP53 (0.69) | NR1I2TDP1MEN1KMT2ATP53 | |
| SCHEMBL6907864 | 0.81 | NR1I2 (0.75) | NR1I2TDP1MEN1KMT2ATP53 | |
| SCHEMBL8204724 | 0.81 | ALDH1A1 (0.71) | NR1I2TDP1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032169-A | Antidotes for herbicides | CIBA-GEIGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| US-4759789-A | Treating locus of plant before or during application of herbicide with oxime ether compound | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| US-4698091-A | 2-phenylpyrimidines, 2-naphthylpyrimidines and 2-heterocyclylpyrimidines as safeners for protecting cultivated plant against phytotoxic damage caused by herbicides | CIBA-GEIGY CORPORATION (US) | 1987-10-06 | — | — | US | disclosed |
| US-4648895-A | ANTIDOTES | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4566901-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0092517-A1 | Oxime ethers, process for their preparation, agents containing these compounds and their use | CIBA-GEIGY AG (CH) | 1983-10-26 | — | — | EP | disclosed |