Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.40 |
| ▸ | F2R | P25116 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799676 | 0.86 | GABRP (0.40) | ITGB3ITGA2BF2RALDH1A1MMP2 | |
| SCHEMBL9799584 | 0.79 | MAPT (0.34) | ITGB3ITGA2BF2RALDH1A1SMN1; SMN2 | |
| SCHEMBL9799808 | 0.78 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MMP2MMP9 | |
| SCHEMBL8260874 | 0.76 | TDP1 (0.36) | ALDH1A1MMP2MMP9GABRA1GABRA5 | |
| SCHEMBL9345623 | 0.75 | GABRP (0.38) | ITGB3ITGA2BF2RALDH1A1MMP2 | |
| Nitric Acid SCHEMBL9344153 | 0.74 | TDP1 (0.33) | ALDH1A1MMP2MMP9GABRA1TSHR | |
| SCHEMBL805212 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL2637184 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL689749 | 0.74 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL9762430 | 0.72 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | disclosed |