Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7389000 | 0.86 | MEN1 (0.45) | SYKMEN1KMT2AMAPTCTSS | |
| SCHEMBL9073508 | 0.86 | MEN1 (0.45) | SYKMEN1KMT2AMAPTCTSS | |
| SCHEMBL8931457 | 0.78 | SYK (0.44) | SYKMEN1KMT2AMAPTCTSS | |
| SCHEMBL16670771 | 0.76 | KEAP1 (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL10381912 | 0.74 | LTA4H (0.50) | SYKMAPTLTA4HCTSSPPARA | |
| SCHEMBL1151094 | 0.74 | MEN1 (0.56) | SYKMEN1KMT2ACTSSPPARA | |
| SCHEMBL7485771 | 0.74 | SYK (0.48) | SYKMEN1KMT2ACTSSPPARA | |
| SCHEMBL11337810 | 0.74 | PTPRB (0.46) | SYKMEN1KMT2AMAPTCTSS | |
| SCHEMBL3619287 | 0.71 | PTPN2 (0.53) | SYKMEN1KMT2ACTSSCTSK | |
| SCHEMBL1151458 | 0.71 | SYK (0.53) | SYKMEN1KMT2AMAPTCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053488-A | Gene expression of human hormones | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY & MEDICINE (AU) | 1991-10-01 | — | — | US | disclosed |
| EP-0112149-B1 | MOLECULAR CLONING AND CHARACTERIZATION OF A FURTHER GENE SEQUENCE CODING FOR HUMAN RELAXIN | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 1991-04-10 | — | — | EP | disclosed |
| EP-0267629-A2 | Polypeptides having interleukin-1 activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-05-18 | — | — | EP | disclosed |
| EP-0112149-A2 | Molecular cloning and characterization of a further gene sequence coding for human relaxin | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 1984-06-27 | — | — | EP | disclosed |