Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073508 | 0.86 | MEN1 (0.45) | KMT2AMEN1MAPT | |
| SCHEMBL7389000 | 0.86 | MEN1 (0.45) | KMT2AMEN1MAPT | |
| SCHEMBL8931457 | 0.79 | SYK (0.44) | KMT2AMEN1MAPT | |
| SCHEMBL9800219 | 0.76 | SYK (0.43) | KMT2AMEN1MAPT | |
| SCHEMBL29501866 | 0.74 | L3MBTL1 (0.42) | KEAP1NFE2L2HPGDCYP1A2CYP3A4 | |
| SCHEMBL10382701 | 0.72 | SYK (0.43) | KMT2AMEN1MAPT | |
| SCHEMBL9553926 | 0.70 | CTSK (0.38) | MAPT | |
| SCHEMBL9553930 | 0.70 | CTSK (0.38) | MAPT | |
| SCHEMBL29454707 | 0.70 | DGAT1 (0.34) | KMT2APKMMEN1 | |
| SCHEMBL4951632 | 0.70 | L3MBTL1 (0.41) | KMT2APKMMEN1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015061412-A1 | METHODS AND COMPOSITIONS FOR PROMOTING BRONCHIOLI DILATATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-04-30 | — | — | WO | disclosed |