Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961 | 0.77 | CA1 (0.50) | KDM4EPOLBALDH1A1HPGDCA1 | |
| SCHEMBL12999906 | 0.77 | CA1 (0.50) | KDM4EPOLBALDH1A1HPGDCA1 | |
| SCHEMBL10073449 | 0.74 | MAPT (0.47) | ALDH1A1HPGDCA1CA2L3MBTL1 | |
| SCHEMBL10077999 | 0.73 | ESR2 (0.53) | SMN1; SMN2KDM4EPOLBALDH1A1CA1 | |
| SCHEMBL10073451 | 0.73 | CA1 (0.66) | SMN1; SMN2KDM4EALDH1A1HPGDCA1 | |
| SCHEMBL78695 | 0.71 | ACHE (0.58) | SMN1; SMN2ALDH1A1HPGDCA1CA2 | |
| SCHEMBL10224439 | 0.70 | ALDH1A1 (0.42) | KDM4EPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL12358544 | 0.69 | ALDH1A1 (0.63) | KDM4EALDH1A1TDP1LMNANPC1 | |
| SCHEMBL10258334 | 0.69 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1CA1CA2CA12 | |
| SCHEMBL383820 | 0.69 | ALDH1A1 (0.66) | SMN1; SMN2KDM4EPOLBAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045542-A | Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives | SCHERING CORPORATION (US) | 1991-09-03 | — | — | US | disclosed |