Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12999906 | 0.92 | CA1 (0.50) | ACHECA12CA1CA2CA7 | |
| SCHEMBL7961 | 0.92 | CA1 (0.50) | ACHECA12CA1CA2CA7 | |
| SCHEMBL10077999 | 0.83 | ESR2 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26234450 | 0.81 | MAPT (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13686360 | 0.80 | HTT (0.49) | SMN1; SMN2ALDH1A1KMT2AMAPTGAA | |
| SCHEMBL14012625 | 0.79 | CA1 (0.41) | ACHECA12CA1CA2CA7 | |
| SCHEMBL10224439 | 0.79 | ALDH1A1 (0.42) | ACHECA12CA1CA2CA7 | |
| SCHEMBL23664313 | 0.79 | APP (0.38) | ACHECA12CA1CA2CA7 | |
| SCHEMBL12358544 | 0.79 | ALDH1A1 (0.63) | RELARAB9ANPC1ALDH1A1ALOX5 | |
| SCHEMBL10258334 | 0.79 | ALDH1A1 (0.41) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180193365-A1 | USE OF HYDROGEN SULFIDE TO PREVENT LENS OPACIFICATION | CREIGHTON UNIV (US) | 2018-07-12 | — | — | US | disclosed |
| US-20180162813-A1 | MIF MODULATORS | YALE UNIVERSITY | 2018-06-14 | — | — | US | disclosed |
| US-9944607-B2 | Thiohydantoin derivatives and uses thereof | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2018-04-17 | — | — | US | disclosed |
| US-9907854-B2 | Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof | CellMosaic, Inc. (US) | 2018-03-06 | — | — | US | disclosed |
| US-9862734-B2 | Metal-ligand complex, olefin polymerization catalyst derived therefrom, and olefin polymerization method utilizing the catalyst | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-09 | — | — | US | disclosed |
| US-9643984-B2 | Method for the preparation of [1,2,4]-triazolo[4,3-a]pyridines | AMGEN INC. (US) | 2017-05-09 | — | — | US | disclosed |
| US-20170065726-A1 | NOVEL CROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC BIOCONJUGATES, AND SYNTHETIC METHODS THEREOF | CELLMOSAIC INC (US) | 2017-03-09 | — | — | US | disclosed |
| US-9540322-B2 | MIF modulators | YALE UNIVERSITY (US) | 2017-01-10 | — | — | US | disclosed |
| US-9511150-B2 | Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof | CellMosaic, Inc. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160347769-A1 | METHOD FOR THE PREPARATION OF [1,2,4]-TRIAZOLO[4,3-A]PYRIDINES | AMGEN INC. | 2016-12-01 | — | — | US | disclosed |
| US-20110245210-A1 | THALIDOMIDE ANALOGS | The Government of the United States of America, as represented by the Secretary of | 2011-10-06 | — | — | US | disclosed |
| US-20110172186-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. | 2011-07-14 | — | — | US | disclosed |
| US-20110155247-A1 | Organic Semiconductors and Devices Incorporating Same | FLEXTERRA, INC. | 2011-06-30 | — | — | US | disclosed |
| US-20110130368-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2011-06-02 | — | — | US | disclosed |
| US-20110098257-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | ANTIBE THERAPEUTICS INC. (CA) | 2011-04-28 | — | — | US | disclosed |
| US-20110046066-A1 | INHIBITORS OF IAP | GENENTECH, INC. (US) | 2011-02-24 | — | — | US | disclosed |
| US-20110039820-A1 | LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-02-17 | — | — | US | disclosed |
| US-7741348-B2 | Bisheterocycle tandem compounds useful as antiviral agents, the uses thereof and the compositions comprising such compounds | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2010-06-22 | — | — | US | disclosed |
| EP-1902050-B1 | OXAZOLIDINONE DERIVATIVES AND USE THEREOF AS ANTIBIOTICS | FERRER INT (ES) | 2009-09-09 | — | — | EP | disclosed |
| US-20080306121-A1 | Bisheterocycle Tandem Compounds Useful as Antiviral Agents, the Uses Thereof and the Compositions Comprising Such Compounds | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110155247-A1 | Organic Semiconductors and Devices Incorporating Same | TST, DDT, TEC | ACHE 286/4885RELA 2932/4885CA12 2443/4885 |
| US-20180193365-A1 | USE OF HYDROGEN SULFIDE TO PREVENT LENS OPACIFICATION | CRYZ, CBS, CRYAA | ACHE 1360/4885RELA 2157/4885CA12 652/4885 |
| US-20110172186-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, ASAH1 | ACHE 445/4885RELA 2878/4885CA12 2134/4885 |
| US-20110098257-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | CBS, SI, APC | ACHE 3320/4885RELA 377/4885CA12 1411/4885 |
| US-20180162813-A1 | MIF MODULATORS | MIF, HMGB2, HMGB3 | ACHE 4704/4885RELA 178/4885CA12 3086/4885 |
| US-20110039820-A1 | LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS | PRKCI, PIK3CA, AKT1 | ACHE 2026/4885RELA 1340/4885CA12 4405/4885 |
| US-20110046066-A1 | INHIBITORS OF IAP | BIRC5, XIAP, BIRC3 | ACHE 2684/4885RELA 803/4885CA12 3717/4885 |
| US-20170065726-A1 | NOVEL CROSSLINKING REAGENTS, MACROMOLECULES, THERAPEUTIC BIOCONJUGATES, AND SYNTHETIC METHODS THEREOF | CD44, ADH1C, EPCAM | ACHE 4005/4885RELA 3820/4885CA12 652/4885 |
| US-20080306121-A1 | Bisheterocycle Tandem Compounds Useful as Antiviral Agents, the Uses Thereof and the Compositions Comprising Such Compounds | PCNA, HAVCR2, HCCS | ACHE 4544/4885RELA 2491/4885CA12 3872/4885 |
| US-20110130368-A1 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID | CBS, SI, APC | ACHE 3320/4885RELA 377/4885CA12 1411/4885 |
| US-20110245210-A1 | THALIDOMIDE ANALOGS | TNF, TNFRSF1A, PGF | ACHE 2452/4885RELA 15/4885CA12 2950/4885 |
| US-20160347769-A1 | METHOD FOR THE PREPARATION OF [1,2,4]-TRIAZOLO[4,3-A]PYRIDINES | H1-4, H1-5, H1-3 | ACHE 1140/4885RELA 4431/4885CA12 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.