SCHEMBL9800244

SCHEMBL9800244

CCOC1CC(C)CC(=O)N1C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7657267 0.83
SCHEMBL26750315 0.70 KMT2A (0.37)
SCHEMBL9800228 0.69 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL9800254 0.68 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL9800222 0.68
SCHEMBL9800257 0.67 KMT2A (0.34)
SCHEMBL7663804 0.66 GAA (0.36) ALDH1A1SMN1; SMN2
SCHEMBL7663878 0.64 GAA (0.43) ALDH1A1SMN1; SMN2
SCHEMBL9800221 0.64 HTR1A (0.32) ALDH1A1SMN1; SMN2
SCHEMBL11486738 0.62 CRBN (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417143-A1 CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL THE UPJOHN COMPANY (US) 1991-03-20 EP claimed
WO-1989011856-A2 CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL THE UPJOHN COMPANY (US) 1989-12-14 WO claimed
EP-0417143-A1 CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL THE UPJOHN COMPANY (US) 1991-03-20 EP disclosed
WO-1989011856-A2 CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL THE UPJOHN COMPANY (US) 1989-12-14 WO disclosed