Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800221 | 0.80 | HTR1A (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7657267 | 0.75 | — | — | |
| SCHEMBL9800242 | 0.74 | — | — | |
| SCHEMBL9800243 | 0.69 | MAPT (0.34) | ALDH1A1PLA2G7MAPT | |
| SCHEMBL9800228 | 0.69 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9800244 | 0.68 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16395804 | 0.67 | MAPT (0.35) | ALDH1A1PLA2G7MAPT | |
| SCHEMBL9800302 | 0.67 | — | — | |
| SCHEMBL9800234 | 0.63 | SRD5A1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11738006 | 0.62 | MAPT (0.35) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417143-A1 | CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL | THE UPJOHN COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1989011856-A2 | CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL | THE UPJOHN COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |