Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.59 |
| ▸ | HTR1D | P28221 | 6/20 | 0.59 |
| ▸ | HTR1B | P28222 | 6/20 | 0.59 |
| ▸ | HTR2A | P28223 | 4/20 | 0.59 |
| ▸ | HTR5A | P47898 | 3/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HTR1E | P28566 | 1/20 | 0.59 |
| ▸ | HTR1F | P30939 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | HTR3A | P46098 | 1/20 | 0.59 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MPO | P05164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9800399 | 0.98 | HTR1A (0.57) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL9800346 | 0.89 | MPO (0.57) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL2739183 | 0.89 | HTR1D (0.74) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL9800384 | 0.88 | HTR1D (0.59) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL9800335 | 0.88 | HTR1A (0.61) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| Hydrochloric Acid SCHEMBL9800419 | 0.87 | MPO (0.57) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL9800344 | 0.87 | MTNR1A (0.62) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL9800349 | 0.85 | HTR1A (0.80) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL9800369 | 0.85 | HTR1A (0.57) | HTR1AHTR1DHTR1BHTR2AHTR5A | |
| SCHEMBL9800342 | 0.85 | HTR2A (0.54) | HTR1AHTR1DHTR1BHTR2AHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |