Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800350 | 0.87 | ADRB2 (0.43) | ADRB2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9800333 | 0.84 | NQO2 (0.42) | ADRB2NQO2MTNR1AMTNR1BSPR | |
| Hydrochloric Acid SCHEMBL9800409 | 0.82 | NQO2 (0.41) | ADRB2NQO2MTNR1AMTNR1BSPR | |
| SCHEMBL9800340 | 0.81 | HTR1D (0.54) | ADRB2NQO2MTNR1AMTNR1BSPR | |
| SCHEMBL9800355 | 0.80 | HTR6 (0.55) | ADRB2HTR1DHTR6CYP19A1 | |
| SCHEMBL9800394 | 0.79 | ADRB2 (0.41) | ADRB2NQO2MTNR1AMTNR1BSPR | |
| Hydrochloric Acid SCHEMBL9800379 | 0.79 | HTR6 (0.54) | ADRB2HTR1DHTR6CYP19A1 | |
| SCHEMBL9800377 | 0.78 | ADRB2 (0.46) | ADRB2NQO2MTNR1AMTNR1BSPR | |
| Hydrochloric Acid SCHEMBL9800411 | 0.78 | HTR6 (0.53) | ADRB2HTR1DHTR6CYP19A1 | |
| SCHEMBL10494828 | 0.77 | ADRB2 (0.44) | ADRB2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994483-A | 5-substituted-3-aminoalkyl indole derivatives for migraine | GLAXO GROUP LIMITED (GB) | 1991-02-19 | — | — | US | disclosed |