Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915143 | 0.76 | — | — | |
| SCHEMBL13273026 | 0.75 | CYP3A4 (0.33) | SMN1; SMN2HPGD | |
| SCHEMBL2224518 | 0.66 | USP2 (0.47) | CTSKSMN1; SMN2HPGD | |
| SCHEMBL9852425 | 0.66 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGD | |
| SCHEMBL2634417 | 0.64 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL5185418 | 0.62 | ALDH1A1 (0.36) | SMN1; SMN2POLB | |
| SCHEMBL12144120 | 0.59 | HRH3 (0.38) | — | |
| SCHEMBL1336951 | 0.57 | TSHR (0.39) | CTSKSMN1; SMN2 | |
| SCHEMBL31678956 | 0.55 | ANPEP (0.36) | CTSK | |
| SCHEMBL1721269 | 0.55 | FAAH (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |