⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653895 | 0.89 | — | — | |
| SCHEMBL9515524 | 0.72 | THRB (0.37) | — | |
| SCHEMBL28545353 | 0.70 | — | — | |
| SCHEMBL28898034 | 0.69 | — | — | |
| SCHEMBL9653161 | 0.66 | — | — | |
| SCHEMBL10851002 | 0.65 | HSD17B10 (0.34) | — | |
| SCHEMBL9800580 | 0.65 | HSD17B10 (0.34) | — | |
| SCHEMBL9516571 | 0.65 | HSD17B10 (0.34) | — | |
| SCHEMBL9516662 | 0.65 | HSD17B10 (0.34) | — | |
| Bicarbonate SCHEMBL18886535 | 0.64 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415939-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-03-13 | — | — | EP | disclosed |
| WO-1989009218-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-10-05 | — | — | WO | disclosed |