Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14021995 | 0.84 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2NPC1RAB9ASCN9A | |
| SCHEMBL29612552 | 0.83 | PPARG (0.56) | MAPTALDH1A1ATMHTTKDM4E | |
| SCHEMBL23063015 | 0.83 | PPARG (0.56) | MAPTALDH1A1ATMHTTKDM4E | |
| SCHEMBL2000772 | 0.82 | PPARG (0.54) | MAPTALDH1A1ATMHTTKDM4E | |
| SCHEMBL1913888 | 0.81 | LMNA (0.62) | MAPTALDH1A1HTTCASP1HSD17B10 | |
| SCHEMBL9800721 | 0.81 | ALDH1A1 (0.66) | MAPTALDH1A1ATMHTTKDM4E | |
| SCHEMBL3821627 | 0.80 | ALDH1A1 (0.49) | MAPTALDH1A1ATMHTTKDM4E | |
| SCHEMBL9800655 | 0.79 | KMT2A (0.64) | MAPTALDH1A1HTTKDM4EHSP90AA1 | |
| SCHEMBL10655058 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1ATMHTTKDM4E | |
| SCHEMBL9447156 | 0.77 | GAA (0.66) | MAPTALDH1A1ATMHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |