Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 9/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446946 | 0.88 | PGR (0.62) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL6981076 | 0.84 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL9800662 | 0.84 | NR3C1 (0.52) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL9446979 | 0.83 | SLC40A1 (0.55) | ALDH1A1MEN1KMT2APPARGCYP3A4 | |
| SCHEMBL9446984 | 0.81 | MEN1 (0.71) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL9447120 | 0.80 | PGR (0.62) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL10650414 | 0.79 | AR (0.55) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL9800657 | 0.78 | FFAR4 (0.62) | ALDH1A1KMT2AGAAPPARGCYP3A4 | |
| SCHEMBL3822856 | 0.77 | PPARG (0.51) | ALDH1A1MEN1KMT2APPARGCYP3A4 | |
| SCHEMBL10654161 | 0.77 | GAA (0.60) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |