Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796854 | 0.87 | HPGD (0.47) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL6691919 | 0.85 | NOTUM (0.60) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL13002995 | 0.85 | HPGD (0.46) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL20897098 | 0.85 | RAB9A (0.47) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL25014859 | 0.82 | MEN1 (0.54) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL13309261 | 0.82 | HTR2A (0.45) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL13309263 | 0.82 | RAB9A (0.45) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL12919995 | 0.82 | ALDH1A1 (0.54) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL19193156 | 0.79 | ALDH1A1 (0.43) | HPGDRAB9ANPC1NOTUMALDH1A1 | |
| SCHEMBL9800936 | 0.78 | LMNA (0.47) | HPGDRAB9AALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185762-B1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0185762-A4 | CELL-DELIVERY AGENT. | DANA FARBER CANCER INST INC (US) | 1986-12-01 | — | — | EP | disclosed |
| US-4625014-A | Cell-delivery agent | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0185762-A1 | CELL-DELIVERY AGENT. | DANA FARBER CANCER INST INC (US) | 1986-07-02 | — | — | EP | disclosed |
| WO-1986000527-A1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-01-30 | — | — | WO | disclosed |