Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29216430 | 0.92 | NOTUM (0.52) | NOTUMHPGDRAB9ANPC1MAPT | |
| SCHEMBL27796854 | 0.87 | HPGD (0.47) | NOTUMHPGDRAB9ANPC1MAPT | |
| SCHEMBL13002995 | 0.85 | HPGD (0.46) | NOTUMHPGDRAB9ANPC1MAPT | |
| SCHEMBL9800935 | 0.85 | HPGD (0.46) | NOTUMHPGDRAB9ANPC1MAPT | |
| SCHEMBL25014859 | 0.85 | MEN1 (0.54) | NOTUMHPGDRAB9ANPC1ALDH1A1 | |
| SCHEMBL12919995 | 0.85 | ALDH1A1 (0.54) | NOTUMHPGDRAB9ANPC1MAPT | |
| SCHEMBL13309263 | 0.85 | RAB9A (0.45) | NOTUMHPGDRAB9ANPC1MAPT | |
| SCHEMBL13309261 | 0.85 | HTR2A (0.45) | NOTUMHPGDRAB9ANPC1MAPT | |
| SCHEMBL20897098 | 0.82 | RAB9A (0.47) | NOTUMHPGDRAB9ANPC1MAPT | |
| SCHEMBL19193156 | 0.81 | ALDH1A1 (0.43) | NOTUMHPGDRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343694-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | KOREA RESERARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2024-10-17 | — | — | US | disclosed |
| EP-4382514-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2024-06-12 | — | — | EP | disclosed |
| CN-118139847-A | Pyrimidine derivatives, process for preparing the same, and pharmaceutical composition for preventing or treating cancer comprising the same as active ingredient | 韩国化学研究院 | 2024-06-04 | — | — | CN | disclosed |
| EP-4371983-A1 | NOVEL PYRIMIDINE-2,4-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | Korea Research Institute of Chemical Technology (KR) | 2024-05-22 | — | — | EP | disclosed |
| CN-117794914-A | Pyrimidine-2, 4-diamine derivatives, process for preparing the same, and pharmaceutical composition for preventing or treating cancer comprising the same as active ingredient | 韩国化学研究院 | 2024-03-29 | — | — | CN | disclosed |
| US-20230346942-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| WO-2023287130-A1 | NOVEL PYRIMIDINE-2,4-DIAMINE DERIVATIVES, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | 한국화학연구원 | 2023-01-19 | — | — | WO | disclosed |
| US-20110028350-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | AFFYMETRIX, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20110028350-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | AFFYMETRIX, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20100324266-A1 | Photocleavable Protecting Groups | AFFYMETRIX, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| US-7737169-B2 | Anionically substituted 7-nitroindoline derivatives and their uses | MEDICAL RESEARCH COUNCIL (GB) | 2010-06-15 | — | — | US | disclosed |
| US-20090076295-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | AFFYMETRIX, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| US-20090076295-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | AFFYMETRIX, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| US-20070203099-A1 | Anionically substituted 7-nitroindoline derivatives and their uses | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2007-08-30 | — | — | US | disclosed |
| WO-2004085394-A1 | 7-NITROINDOLINE DERIVATIVES AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324266-A1 | Photocleavable Protecting Groups | POLL, PCNA, ERCC4 | NOTUM 1719/4885HPGD 3765/4885RAB9A 3825/4885 |
| US-20070203099-A1 | Anionically substituted 7-nitroindoline derivatives and their uses | SLC18A3, SLC18A1, SLC18A2 | NOTUM 4240/4885HPGD 265/4885RAB9A 550/4885 |
| US-20090076295-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | POLL, PCNA, ERCC4 | NOTUM 1719/4885HPGD 3765/4885RAB9A 3825/4885 |
| US-20240343694-A1 | PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | ERBB2, EGFR, DPYD | NOTUM 228/4885HPGD 319/4885RAB9A 3780/4885 |
| US-20110028350-A1 | PHOTOCLEAVABLE PROTECTING GROUPS | POLL, ERCC5, FBL | NOTUM 900/4885HPGD 3679/4885RAB9A 3806/4885 |
| US-20230346942-A1 | MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF | CRY1, MAPT, PYGL | NOTUM 3190/4885HPGD 292/4885RAB9A 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.