Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821937 | 0.85 | DRD2 (0.35) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL21567209 | 0.84 | KDM4E (0.32) | SIGMAR1 | |
| SCHEMBL9801382 | 0.83 | ALOX15 (0.46) | SIGMAR1 | |
| SCHEMBL9801193 | 0.83 | MAPK1 (0.39) | SIGMAR1 | |
| SCHEMBL9801163 | 0.81 | SIGMAR1 (0.36) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL9801642 | 0.80 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL22326402 | 0.80 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL9801794 | 0.80 | KEAP1 (0.38) | SIGMAR1 | |
| SCHEMBL9801669 | 0.79 | SIGMAR1 (0.35) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL18272345 | 0.76 | CYP1A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099761-B1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-27 | — | — | EP | disclosed |
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |