Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9801817 | 0.95 | KEAP1 (0.36) | KEAP1SMN1; SMN2SIGMAR1L3MBTL1CYP2D6 | |
| SCHEMBL9801762 | 0.93 | SIGMAR1 (0.37) | KEAP1SMN1; SMN2SIGMAR1L3MBTL1CYP2D6 | |
| SCHEMBL9801496 | 0.92 | SIGMAR1 (0.40) | KEAP1SMN1; SMN2SIGMAR1L3MBTL1 | |
| SCHEMBL9801740 | 0.91 | KEAP1 (0.36) | KEAP1SMN1; SMN2SIGMAR1L3MBTL1CYP2D6 | |
| SCHEMBL9801737 | 0.90 | SIGMAR1 (0.39) | SIGMAR1L3MBTL1 | |
| SCHEMBL24533504 | 0.86 | BCHE (0.32) | SIGMAR1BCHE | |
| SCHEMBL9801426 | 0.85 | ALOX15 (0.44) | SIGMAR1L3MBTL1ALOX15 | |
| SCHEMBL9801005 | 0.84 | L3MBTL1 (0.34) | KEAP1SMN1; SMN2SIGMAR1L3MBTL1 | |
| SCHEMBL9801794 | 0.84 | KEAP1 (0.38) | KEAP1SMN1; SMN2SIGMAR1CYP2D6HSD17B10 | |
| SCHEMBL9801533 | 0.83 | SIGMAR1 (0.41) | SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992150-A | Telomer with alpha-olefin;oil and fuel additive | NIPPON OIL CO, LTD. (JP) | 1991-02-12 | — | — | US | disclosed |