Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878508 | 0.79 | AKR1C3 (0.71) | AKR1C3AKR1C1NPC1RAB9AALDH1A1 | |
| SCHEMBL6004247 | 0.74 | AKR1C3 (0.64) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL4675007 | 0.74 | AKR1C3 (0.44) | AKR1C3AKR1C1HSD11B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23012370 | 0.73 | AKR1C3 (0.52) | AKR1C3AKR1C1NPC1RAB9AALDH1A1 | |
| SCHEMBL4252110 | 0.73 | ALDH1A1 (0.47) | AKR1C3AKR1C1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4677344 | 0.71 | AKR1C3 (0.50) | AKR1C3AKR1C1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6004358 | 0.69 | AKR1C3 (0.47) | AKR1C3AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL786733 | 0.69 | GABRA2 (0.43) | CNR2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL2762763 | 0.66 | ALDH1A1 (0.66) | AKR1C3AKR1C1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27430260 | 0.66 | ALDH1A1 (0.50) | AKR1C3AKR1C1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417556-A2 | Positive-working radiation-sensitive mixture and recording material prepared therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | disclosed |