Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83496 | 0.85 | CYP2C19 (0.44) | KMT2ATSHRALDH1A1CRHBPCRHR2 | |
| SCHEMBL17075279 | 0.84 | KEAP1 (0.46) | L3MBTL1SMN1; SMN2KEAP1NFE2L2CYP2C19 | |
| SCHEMBL17800251 | 0.79 | CRHBP (0.41) | KMT2ATSHRALDH1A1LMNAMAPT | |
| Adipic Acid SCHEMBL27731397 | 0.77 | KMT2A (0.61) | L3MBTL1KMT2ATSHRALDH1A1LMNA | |
| Adipic Acid SCHEMBL3804252 | 0.77 | KMT2A (0.61) | L3MBTL1KMT2ATSHRALDH1A1LMNA | |
| Azelaic Acid SCHEMBL3807504 | 0.75 | TSHR (0.60) | L3MBTL1KMT2ATSHRALDH1A1LMNA | |
| Sebacic Acid SCHEMBL28279615 | 0.75 | TSHR (0.60) | L3MBTL1KMT2ATSHRALDH1A1LMNA | |
| P-Xylene SCHEMBL36101 | 0.75 | TSHR (0.60) | L3MBTL1KMT2ATSHRALDH1A1LMNA | |
| Sebacic Acid SCHEMBL36102 | 0.75 | TSHR (0.60) | L3MBTL1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL7145665 | 0.75 | TAS2R14 (0.46) | L3MBTL1KMT2ATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255595-B1 | METHOD FOR PRODUCING MOULDED LOW-TENSION COMPONENTS | BAYER AG (DE) | 1991-12-27 | — | — | EP | disclosed |
| EP-0254174-B1 | USE OF CURABLE REACTIVE MASSES IN THE PREPARATION OF SUPPORT OF DATA | BAYER AG (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0254184-B1 | USE OF CURABLE REACTIVE MASSES IN THE PREPARATION OF DATA SUPPORTS | BAYER AG (DE) | 1991-03-13 | — | — | EP | disclosed |
| US-4908216-A | Apparatus for the production of low tension moulded parts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |