Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613008 | 0.87 | ACHE (0.44) | ACHEKDM4EALDH1A1HPGDIMPDH2 | |
| Hydrochloric Acid SCHEMBL9802508 | 0.75 | ACHE (0.40) | ACHESLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL9448055 | 0.70 | SIGMAR1 (0.41) | ACHEPGRARKDM4EALDH1A1 | |
| SCHEMBL14939214 | 0.70 | ACHE (0.62) | ACHESLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL9520586 | 0.67 | ACHE (0.54) | ACHESLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL7310836 | 0.65 | ACHE (0.43) | ACHEKDM4EALDH1A1HPGDCA1 | |
| SCHEMBL9802750 | 0.64 | SLC6A2 (0.44) | ACHESLC6A2SLC6A4SLC6A3NR3C1 | |
| SCHEMBL8057572 | 0.64 | NOS3 (0.57) | ACHESLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL6541540 | 0.64 | ACHE (0.54) | ACHESLC6A2SLC6A4SLC6A3KDM4E | |
| Hydrochloric Acid SCHEMBL9802505 | 0.63 | SLC6A2 (0.43) | ACHESLC6A2SLC6A4SLC6A3NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994486-A | Neurological disorders | ABBOTT LABORATORIES (US) | 1991-02-19 | — | — | US | disclosed |