Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24205150 | 0.79 | KMT2A (0.42) | KMT2AMEN1ALDH1A1HSD17B13LMNA | |
| SCHEMBL8876423 | 0.78 | KDM4E (0.42) | ALDH1A1HSD17B13LMNAADORA2AADORA2B | |
| SCHEMBL4145685 | 0.76 | ADORA2A (0.39) | ALDH1A1ADORA2AADORA2BKDM4EMAPT | |
| SCHEMBL13384442 | 0.73 | GSK3A (0.34) | ALDH1A1ADORA2AADORA2BKDM4EMAPT | |
| SCHEMBL7516778 | 0.73 | ADORA2A (0.35) | ALDH1A1ADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL10656238 | 0.73 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1LMNAADORA2A | |
| SCHEMBL27506471 | 0.72 | POLB (0.39) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL11502128 | 0.72 | KMT2A (0.38) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL1953767 | 0.72 | KMT2A (0.38) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL19147865 | 0.72 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1LMNAADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299413-B1 | New tetramethyl-cis-diaza-bicyclo[4.2.0]octane-3,5-dione derivatives having a differentiation-inducing activity | MEIJI SEIKA KAISHA LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |
| US-4939156-A | Antitumor agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0299413-A1 | New tetramethyl-cis-diaza-bicyclo[4.2.0]octane-3,5-dione derivatives having a differentiation-inducing activity | MEIJI SEIKA KAISHA LTD. (JP) | 1989-01-18 | — | — | EP | disclosed |