Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | LITAF | Q99732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876423 | 0.75 | KDM4E (0.42) | ADORA2AADORA2BALDH1A1GAAHTT | |
| SCHEMBL9802893 | 0.73 | KMT2A (0.41) | ADORA2APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL4145685 | 0.73 | ADORA2A (0.39) | ADORA2APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL13384442 | 0.70 | GSK3A (0.34) | ADORA2APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL27506471 | 0.70 | POLB (0.39) | ALDH1A1GAAHTTGSK3AGSK3B | |
| SCHEMBL14968971 | 0.69 | LMNA (0.46) | ALDH1A1HTTMAPK8 | |
| SCHEMBL20369245 | 0.64 | ALDH1A1 (0.42) | ADORA2APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL13932146 | 0.64 | PDE4A (0.49) | PDE4BPDE4DPDE4APDE4CGSK3A | |
| SCHEMBL23505982 | 0.63 | GABRA5 (0.35) | ADORA2APDE4BPDE4DPDE4APDE4C | |
| SCHEMBL26820684 | 0.63 | FFAR4 (0.34) | ADORA2APDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080071-A4 | A PROCESS FOR PRODUCING AN ORGANIC TRISULFIDE COMPOUND | PHILLIPS PETROLEUM CO (US) | 2002-06-26 | — | — | EP | claimed |
| EP-1080071-A1 | A PROCESS FOR PRODUCING AN ORGANIC TRISULFIDE COMPOUND | Phillips Petroleum Company (US) | 2001-03-07 | — | — | EP | claimed |
| WO-1999059965-A1 | A PROCESS FOR PRODUCING AN ORGANIC TRISULFIDE COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1999-11-25 | — | — | WO | claimed |
| EP-2922859-B1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | UNIV CORK (IE) | 2021-05-05 | — | — | EP | disclosed |
| US-9822137-B2 | Phosphonucleosides useful in the treatment of viral disorders | UNIVERSITY COLLEGE CORK (IE) | 2017-11-21 | — | — | US | disclosed |
| US-20150291640-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2015-10-15 | — | — | US | disclosed |
| EP-2922859-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | University College Cork (IE) | 2015-09-30 | — | — | EP | disclosed |
| WO-2014079903-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | UNIVERSITY COLLEGE CORK (IE) | 2014-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291640-A1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | ENTPD5, PNP, MTAP | ADORA2A 2042/4885PDE4B 575/4885PDE4D 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.