Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 5/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LGMN | Q99538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147828 | 0.85 | GSK3B (0.35) | ADORA2AADORA2BALDH1A1GAAKDM4E | |
| SCHEMBL8876423 | 0.78 | KDM4E (0.42) | ADORA2AADORA2BALDH1A1GAAKDM4E | |
| SCHEMBL4150749 | 0.77 | PDE4A (0.42) | ADORA2AADORA2BALDH1A1KDM4EPDE4A | |
| SCHEMBL9802893 | 0.76 | KMT2A (0.41) | ADORA2AADORA2BALDH1A1KDM4EMAPT | |
| SCHEMBL29095246 | 0.76 | EEF2K (0.42) | ADORA2AADORA2BALDH1A1GAAKDM4E | |
| SCHEMBL4156451 | 0.74 | PDE4A (0.43) | ADORA2AADORA2BMAPTPDE4APDE4B | |
| SCHEMBL7516778 | 0.73 | ADORA2A (0.35) | ADORA2AADORA2BALDH1A1GAAPDE4A | |
| SCHEMBL13384442 | 0.73 | GSK3A (0.34) | ADORA2AADORA2BALDH1A1GAAKDM4E | |
| SCHEMBL7196320 | 0.73 | ADORA2B (0.49) | ADORA2AADORA2BGAAPDE4APDE4B | |
| SCHEMBL27506471 | 0.72 | POLB (0.39) | ALDH1A1GAAKDM4EMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048374-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
| EP-1996649-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | Baerlocher GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007104379-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |
| EP-0092398-B1 | SUBSTITUTED 8-PHENYLXANTHINES | WARNER-LAMBERT COMPANY (US) | 1987-03-25 | — | — | EP | disclosed |
| US-4452788-A | BRONCHODILATORS | WARNER-LAMBERT COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0092398-A1 | Substituted 8-phenylxanthines | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | disclosed |