Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19148089 | 0.98 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL19147865 | 0.98 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL19147853 | 0.98 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL19147803 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL7196320 | 0.80 | ADORA2B (0.49) | KMT2AMEN1ADORA2BTNFADORA2A | |
| SCHEMBL24205150 | 0.78 | KMT2A (0.42) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL27700732 | 0.77 | RGS4 (0.42) | ALDH1A1KMT2ALMNAMEN1ADORA2A | |
| SCHEMBL9416281 | 0.77 | TNF (0.42) | ALDH1A1KDM4EMAPTLMNAADORA2B | |
| SCHEMBL14185053 | 0.77 | KMT2A (0.46) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL9416283 | 0.76 | ICMT (0.42) | KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55064575-A | — | — | None | — | — | JP | disclosed |
| WO-2017123823-A1 | ALKYL-, ACYL-, UREA-, AND AZA-URACIL SULFIDE:QUINONE OXIDOREDUCTASE INHIBITORS | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2017-07-20 | — | — | WO | disclosed |
| EP-0265506-A1 | A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER | FARMACEUTISK LABORATORIUM FERRING A/S (DK) | 1988-05-04 | — | — | EP | disclosed |
| WO-1987006581-A1 | A PRODRUG FORM OF 5-FLUOROURACIL AND A METHOD OF TREATMENT OF CANCER | FARMACEUTISK LABORATORIUM FERRING A/S (DK) | 1987-11-05 | — | — | WO | disclosed |
| JP-S5564575-A | PREPARATION OF 3-ACYL-5-FLUOROURACIL | GRELAN PHARMACEUT CO LTD | 1980-05-15 | — | — | JP | disclosed |
| US-4196202-A | Carcinostatic composition containing 3-N-o-toluyl-5-fluorouracil producing the same | OKADA TAIJI | 1980-04-01 | — | — | US | disclosed |
| US-4088646-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-05-09 | — | — | US | disclosed |