Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328468 | 0.85 | MAPT (0.54) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL28800723 | 0.83 | MAPT (0.52) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL15572127 | 0.80 | POLB (0.49) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL9803050 | 0.78 | L3MBTL1 (0.48) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL15572722 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL29750830 | 0.74 | LMNA (0.43) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL22570509 | 0.73 | ALDH1A1 (0.47) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL8127178 | 0.72 | ALDH1A1 (0.46) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL21186930 | 0.72 | ALDH1A1 (0.46) | ALDH1A1ALOX15MAPK1HSD17B10POLB | |
| SCHEMBL26106785 | 0.71 | HSD17B10 (0.53) | ALDH1A1ALOX15MAPK1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385237-B1 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5021421-A | Psychotropic agents | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |