Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983976 | 0.88 | ALDH1A1 (0.33) | ESR1ESR2ALDH1A1CYP3A4NR3C2 | |
| SCHEMBL983284 | 0.86 | ALDH1A1 (0.32) | ESR1ESR2ALDH1A1CYP3A4NR3C2 | |
| SCHEMBL985492 | 0.84 | NR3C2 (0.36) | ESR1ESR2ALDH1A1CYP3A4NR3C2 | |
| SCHEMBL982195 | 0.80 | ESR1 (0.38) | ESR1ESR2ALDH1A1CYP3A4NR3C2 | |
| SCHEMBL11596809 | 0.79 | NOS3 (0.33) | — | |
| SCHEMBL982144 | 0.77 | NR3C2 (0.34) | ESR1ESR2ALDH1A1CYP3A4NR3C2 | |
| SCHEMBL984077 | 0.74 | ESR1 (0.39) | ESR1ESR2ALDH1A1CYP3A4NR3C2 | |
| SCHEMBL984616 | 0.73 | NR3C2 (0.38) | ESR1ESR2ALDH1A1CYP3A4NR3C2 | |
| SCHEMBL983817 | 0.69 | LTA4H (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL288010 | 0.68 | ALDH1A1 (0.37) | ESR1ESR2ALDH1A1CYP3A4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-9233918-B2 | Isocyanate production process | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2275406-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | CPS1, PHGDH, APEH | ESR1 3842/4885ESR2 3685/4885ALDH1A1 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.